Elevated lipid peroxides induced angiogenesis in proliferative diabetic retinopathy

Proliferative diabetic retinopathy.

Association of CXCL12 and CXCR4 Genes Polymorphism with Proliferative Diabetic Retinopathy in Diabetic Patients

Introduction: Patients with diabetes are prone to develop complications related to the retina. So far, several genes have been reported in connection with the progression of retinopathy, and a group of these genes is genes involved in angiogenesis. CXCL12 and CXCR4 genes are among the most important genes in this path, which have been less studied and investigated. The aim of this study was to ...

Heritability of Proliferative Diabetic Retinopathy

OBJECTIVE Diabetic nephropathy clusters in families, suggesting that genetic factors play a role in its pathogenesis. We investigated whether similar clustering exists for proliferative retinopathy in families with two or more siblings with type 1 diabetes. RESEARCH DESIGN AND METHODS The FinnDiane Study has characterized 20% (4,800 patients) of adults with type 1 diabetes in Finland. In 188 ...

Endothelial fenestrae in proliferative diabetic retinopathy.

The ultrastructure of old neovascular preretinal membranes was examined in both eyes of a patient with proliferative diabetic retinopathy treated in one eye with photocoagulation. Membranes in both eyes consisted of a matrix rich in mature collagen surrounding viable new vessels and "ghost vessels." Viable vessels of different calibers frequently showed endothelial fenestrae bridged by diaphrag...

head in patients with proliferative diabetic retinopathy

An anatomical taxonomy for neovascular proliferation of the optic nerve head in patients with proliferative diabetic retinopathy is presented. The technique consists in comparing (A) number of involved quadrants, (B) calibre of vessels, (C) neovascular density, (D) neovascular area, (E) plane of proliferation, and (F) fluorescein angiographic findings. A similar taxonomy is used to describe fib...